{"product_id":"melatonin-3-mg-with-b-6","title":"Melatonin 3 mg with B-6","description":"\u003ch2\u003eMelatonin 3 mg with B-6\u003c\/h2\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eMelatonin capsules contain 3 mg of highest purity melatonin produced under strict Good Manufacturing Practices (GMP) standards\u003c\/p\u003e\n\u003ch3\u003eFunctions\u003c\/h3\u003e\n\u003cp\u003eMelatonin is a natural hormone nutrient that is synthesized from the amino acid tryptophan by the pineal gland in the back of the brain. Melatonin also occurs in small amounts in a variety of foods. In the body, melatonin appears to regulate sleep\/wake cycles, support normal immune function, and protect cells from free radical damage. Most of the research on melatonin has focused on its role in maintaining normal sleep\/wake rhythms. The perception of daylight in the eyes is a signal for the pineal gland to inhibit melatonin synthesis andrelease. At night or in the dark, the body's melatonin production rises. The rise in plasma melatonin is thought to be responsible for bringing on sleep. Nocturnal melatonin production is highest in children and begins to decline from adolescence on until it is virtually absent in the elderly. Melatonin supports normal immune function by helping maintain the activity of circulating natural killer cells. It also has been found to function as an antagonist for stress-induced immunosuppression. Melatonin is considered a potent antioxidant that enters all body cells to help prevent free radical damage. In the brain, melatonin is perhaps the most important physiological antioxidant. Due to its lipid and water-soluble properties, it can freely cross the blood-brain barrier. In vitro studies show that melatonin is more effective than glutathione inscavenging toxic hydroxyl radicals, and also more efficient than vitamin E in neutralizing peroxyl radicals which can induce DNA damage. Furthermore, melatonin stimulates the main antioxidant enzyme of the brain, glutathione peroxidase\u003c\/p\u003e\n\u003ch3\u003eIndications\u003c\/h3\u003e\n\u003cp\u003eMelatonin capsules may be a useful nutritional adjunct for individuals who wish to support the body's pineal gland function\u003c\/p\u003e\n\u003ch3\u003eSupplement Facts\u003c\/h3\u003e\n\u003cdiv class=\"supplement-facts\"\u003e\n\u003cp class=\"serving-size\"\u003e\u003cstrong\u003e1 Tablet Contains\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"supplement-facts-table\" style=\"width:100%; max-width:480px; border-collapse:collapse; margin:12px 0;\"\u003e\u003ctbody\u003e\n\u003ctr style=\"border-bottom:1px solid #e5e5e5;\"\u003e\n\u003ctd style=\"padding:6px 8px 6px 0;\"\u003eVitamin B-6 (as pyridoxine HCl)\u003c\/td\u003e\n\u003ctd style=\"text-align:right; white-space:nowrap; padding:6px 0 6px 16px;\"\u003e\u003cstrong\u003e10 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #e5e5e5;\"\u003e\n\u003ctd style=\"padding:6px 8px 6px 0;\"\u003eMelatonin\u003c\/td\u003e\n\u003ctd style=\"text-align:right; white-space:nowrap; padding:6px 0 6px 16px;\"\u003e\u003cstrong\u003e3 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003cp class=\"other-ingredients\"\u003e\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Dicalcium phosphate, microcrystalline cellulose, modified cellulose gum, vegetable stearin, magnesium stearate, and silica.\u003c\/p\u003e\n\u003cp class=\"allergen-info\"\u003e\u003cem\u003eThis product contains NO sugar, salt, dairy, yeast, wheat, gluten, corn, soy, preservatives, artificial colors or flavors.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSuggested Use\u003c\/h3\u003e\n\u003cp\u003eAs a dietary supplement, adults take 1 tablet 20 minutes before bedtime, or as directed by a healthcare professional. Do not exceed 1 tablet per 24 hours\u003c\/p\u003e\n\u003ch3\u003eSide Effects\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eWarning: USE ONLY AT BEDTIME. Not for use by children under 18 years. If pregnant or using a prescription drug, consult a healthcare professional. Do not take this product if you suffer from an autoimmune disease, depression, diabetes, endocrine disorder or thyroid condition. Do not use this product while operating a motorized vehicle or heavy machinery\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore in a cool, dry place, away from direct light. Keep out of reach of children\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col class=\"references\" start=\"1\" style=\"margin:12px 0; padding-left:24px; list-style-type:decimal;\"\u003e\n\u003cli value=\"1\"\u003eAlvarez B, Dahlitz M, Vignau J, Parkes JD: The delayed sleep phase syndrome: Clinical and investigative findings in 14 patients. J Neurol Neurosurg Psychiatry 1992;55:665- 670\u003c\/li\u003e\n\u003cli value=\"2\"\u003eArmstrong SM, Redman JR: Melatonin: A chronobiotic with anti-aging properties? Med Hypotheses 1991;34:300-309\u003c\/li\u003e\n\u003cli value=\"3\"\u003eBeck-Friis J, Kjellman BF, Aperia B et al: Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome. Acta Psychiatr Scand 1985;71:319-330\u003c\/li\u003e\n\u003cli value=\"4\"\u003eBismar K, Morgensen L, Wetterberg L: Depressed melatonin secretion in patients with nightmares due to beta-adrenoceptor blocking drug. Acta Med Scand 1987;221:155-158\u003c\/li\u003e\n\u003cli value=\"5\"\u003eDahlitz M, Alvarez B, Vignau J et al: Delayed sleep phase syndrome response to melatonin. Lancet 1991;337:1121-1124\u003c\/li\u003e\n\u003cli value=\"6\"\u003eLieberman HR: Behavior, sleep and melatonin. J Neural Transm Suppl 1989;21:233-241\u003c\/li\u003e\n\u003cli value=\"7\"\u003eLissoni P, Barni S, Cattaneo G et al: Clinical results with the pineal hormone melatonin in advanced cancer resistant to standard antitumor therapies. Oncology 1991;48:448-450\u003c\/li\u003e\n\u003cli value=\"8\"\u003eMaestroni GJM, Conti A, Pierpaoli W: Role of the pineal gland in immunity: Circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. J Neuroimmunol 1986;13:19-30\u003c\/li\u003e\n\u003cli value=\"9\"\u003eMaurizi CP: The therapeutic potential for tryptophan and melatonin: possible roles in depression, sleep, Alzheimer's disease and abnormal aging. Med Hypotheses 1990;31:233-242\u003c\/li\u003e\n\u003cli value=\"10\"\u003ePetrie K, Conaglen JV , Thompson L, Chamberlain K: Effect of melatonin on jet lag after long haul flights. Br Med J 1989;298:705-707\u003c\/li\u003e\n\u003cli value=\"11\"\u003ePetrie K, Dawson AG, Thompson L, Brook R: A double-blind trial of melatonin as a treatment for jet lag in international cabin crew. Biol Psychiatry 1993;33:526-530\u003c\/li\u003e\n\u003cli value=\"12\"\u003eWaldhauser F, Weiszenbacher G, Tatzer E et al: Alterations in nocturnal serum melatonin levels in humans with growth and aging. J Clin Endocrinol Metab 1988;66:648-652\u003c\/li\u003e\n\u003cli value=\"13\"\u003eWaldhauser F, Waldhauser M, Lieberman HR et al: Bioavailability of oral melatonin in humans. Neuroendocrinology 1984;39:307-313.4 Melatonin 3 mg with Vitamin B-6\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"My Concierge Pharmacy","offers":[{"title":"Default Title","offer_id":51818525884706,"sku":"10107","price":15.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0928\/9429\/8402\/files\/FrontLabel_9c1a834d-cc3c-4ac6-b698-5292cefd32d4.png?v=1783471419","url":"https:\/\/shop.myconciergepharmacy.com\/es\/products\/melatonin-3-mg-with-b-6","provider":"My Concierge Pharmacy","version":"1.0","type":"link"}