{"product_id":"selenium-200-mcg-as-l-selenomethionine","title":"Selenium 200 mcg as L-Selenomethionine","description":"\u003ch2\u003eSelenium 200 mcg as L-Selenomethionine\u003c\/h2\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eSelenium contains 200 mcg of bioavailable selenium per capsule\u003c\/p\u003e\n\u003ch3\u003eFunctions\u003c\/h3\u003e\n\u003cp\u003eSelenomethionine is an amino acid containing selenium. Selenium is a nutritionally essential trace element for humans and animals. The National Research Council's recommended dietary allowance for selenium in adults ranges from 55 to 75 mcg per day depending on age and gender. In American adults, intakes typically range from 80 to165 mcg\/d. Selenium is a cofactor to about 10 selenoproteins in the body; the most important of these appears to be glutathione peroxidase (GPX). GPX uses glutathione to reduce hydrogen peroxide and thus protect cells and plasma against free radical injury. GPX activity depends on an adequate supply of dietary selenium. Recently, selenium as selenocysteine has been identified in the active center of type 1 and 3 iodothyronine deiodinases, two important enzymes regulating the formation and degradation of the active thyroid hormone, triiodothyronine (T3). Another important selenoprotein appears to be selenoprotein P, but its functions remain unclear. Selenium and vitamin E appear to have synergistic effects, since some signs of vitamin E deficiency in animals can be alleviated by dietary selenium. Dietary selenium is generally well absorbed and utilized in the body. The richest food sources of selenium are seafood and organ meats, followed by muscle meats, cereals and grains, and dairy products. Fruits and vegetables are typically low in selenium, and low selenium status has been reported in vegetarians\u003c\/p\u003e\n\u003ch3\u003eIndications\u003c\/h3\u003e\n\u003cp\u003eSelenium may be a useful dietary adjunct for individuals wishing to supplement with this important trace mineral\u003c\/p\u003e\n\u003ch3\u003eSupplement Facts\u003c\/h3\u003e\n\u003cdiv class=\"supplement-facts\"\u003e\n\u003cp class=\"serving-size\"\u003e\u003cstrong\u003e1 Capsule Contains\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"supplement-facts-table\" style=\"width:100%; max-width:480px; border-collapse:collapse; margin:12px 0;\"\u003e\u003ctbody\u003e\u003ctr style=\"border-bottom:1px solid #e5e5e5;\"\u003e\n\u003ctd style=\"padding:6px 8px 6px 0;\"\u003eSelenium (from high selenium yeast)*\u003c\/td\u003e\n\u003ctd style=\"text-align:right; white-space:nowrap; padding:6px 0 6px 16px;\"\u003e\u003cstrong\u003e200 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e\n\u003cp class=\"other-ingredients\"\u003e\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Gelatin, water (capsules), rice powder, cellulose, magnesium stearate and silica. *From SelenoExcell®, an excellent source of naturally- occurring organic L-selenomethionine. It has been the subject of important clinical studies. SelenoExcell® is a registered trademark of Cypress Systems, Inc.\u003c\/p\u003e\n\u003cp class=\"allergen-info\"\u003e\u003cem\u003eThis product contains NO sugar, salt, dairy, wheat, gluten, corn, soy, preservatives, artificial colors or flavors.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSuggested Use\u003c\/h3\u003e\n\u003cp\u003eAs a dietary supplement, adults take 1 capsule daily with meals, or as directed by a healthcare professional\u003c\/p\u003e\n\u003ch3\u003eSide Effects\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eNo adverse effects have been reported\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore in a cool, dry place, away from direct light. Keep out of reach of children\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col class=\"references\" start=\"1\" style=\"margin:12px 0; padding-left:24px; list-style-type:decimal;\"\u003e\n\u003cli value=\"1\"\u003eKadrabová J, Madaric A, Kováciková Z, Ginter E. Selenium status, plasma zinc, copper, and magnesium in vegetarians. Biol Trace Elem Res 1995;50:13- 24\u003c\/li\u003e\n\u003cli value=\"2\"\u003eLarsen PR, Berry MJ. Nutritional and hormonal regulation of thyroid hormone deiodinases. Annu Rev Nutr 1995;15:323-352\u003c\/li\u003e\n\u003cli value=\"3\"\u003eLehr D. A possible beneficial effect of selenium administration in antiarrhythmic therapy. J Am Coll Nutr 1994;13:496-498\u003c\/li\u003e\n\u003cli value=\"4\"\u003eOlmsted L, Schrauzer GN, Flores-Arce M, Dowd J. Selenium supplementation of symptomatic human immunodeficiency virus infected patients. Biol Trace Elem Res 1989;20:59-65\u003c\/li\u003e\n\u003cli value=\"5\"\u003eRoy M, Kiremidjian-Schumacher L, Wishe HI, Cohen MW, Stotzky G. Supplementation with selenium restores age-related decline in immune cell function. Proc Soc Exp Biol Med 1995;209:369-375\u003c\/li\u003e\n\u003cli value=\"6\"\u003eSun E, Xu H, Liu Q, Zhou J, Zuo P, Wang J. The mechanism for the effect of selenium supplementation on immunity. Biol Trace Elem Res 1995;48:231- 238\u003c\/li\u003e\n\u003cli value=\"7\"\u003eGerhard N. Schrauzer. Selenomethionine: A Review of Its Nutritional Significance, Metabolism and Toxicity1 2Journal of Nutrition. 2000;130:1653- 1656\u003c\/li\u003e\n\u003cli value=\"8\"\u003eYiming Xia, Kristina E Hill, Ping Li, Jiayuan Xu, Dingyou Zhou, Amy K Motley, Li Wang, Daniel W Byrne and Raymond F Burk. Optimization of selenoprotein P and other plasma selenium biomarkers for the assessment of the selenium nutritional requirement: a placebo-controlled double-blind study of selenomethionine supplementation in selenium-deficient Chinese subjects. Am J Clin Nutr doi:10.3945\/ajcn.2010.29642 Selenium 200 mcg as L-Selenomethionine\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"My Concierge Pharmacy","offers":[{"title":"Default Title","offer_id":51818532405538,"sku":"10132","price":17.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0928\/9429\/8402\/files\/FrontLabel_ab2aa257-dfe1-46dc-a239-d9393e1508cf.png?v=1783471542","url":"https:\/\/shop.myconciergepharmacy.com\/es\/products\/selenium-200-mcg-as-l-selenomethionine","provider":"My Concierge Pharmacy","version":"1.0","type":"link"}